Search form

Panther System

Experience freedom and control over your molecular testing workflow like never before with the Panther system from Hologic. This fully automated platform provides test consolidation, random-access sample loading and proven assay chemistry to deliver high performance and results you can trust.


The Panther system provides unprecedented control of workflow, driven by random-access and continuous loading of molecular samples, reagents and consumables. This innovative design enables your lab to improve productivity and accelerate results, ultimately helping enhance patient care, while reducing lab costs.

Created to be a fully automated sample-to-answer instrument, the Panther system eliminates the need for batch processing and automates all aspects of nucleic acid testing on a single, integrated platform. This system combines true walkaway freedom with intuitive design for ease of use. With its extraordinary level of automation, the Panther system improves laboratory productivity and operational efficiencies, promising to transform the world of molecular testing as we know it today.



The Panther system provides unique, innovative and streamlined features.

The only system that gives you control to run:

  • Samples as you choose, random access or batch.
  • Multiple assays on the same patient sample.     
  • HPV, CT/GC and trichomonas simultaneously on a single platform.

Integrated automation, enabling you to maximize productivity and reduce costs:

  • True walkaway freedom — sample-to-answer automation.
  • Run multiple tests from a single sample anytime.
  • Bi-directional LIS interface for streamlined data management.
  • Automated scheduled maintenance, reducing hands-on time.

Frees your lab from the confines of batch testing with:

  • Random access and continuous sample/reagent loading to enable flexible workflow.
  • Load-and-go with unattended results processing.
  • Auto-reflexing for HPV genotyping.
  • Controls or calibrators that are run only once in 24 hours.

Have confidence in your results with:

  • Sample chain-of-custody control (PosID).
  • In-process checks, which reduce operator and system errors.
  • Liquid-level detection and reagent dispense verification.
  • Contamination control.
  • Quality control (Levey-Jennings and prevalence) reporting.

Assays currently available on the Panther system for the US, Canada and EU. Please see your local sales rep or distributor to confirm availability in other countries:

  • Aptima Combo 2 assay for CT/NG.
  • Aptima Trichomonas vaginalis assay.
  • Aptima HPV assay.
  • Aptima HPV 16 18/45 genotyping assay.
  • Aptima CT assay and Aptima GC assay
  • HIV-1 viral load.

Assays are currently in development for the Panther system for the following

  • HBV viral load.
  • HCV viral load.
  • M. genitalium.
  • HSV I/II.
  • Bacterial vaginosis.
  • Candida.

Sample throughput:

  • 3.5 hours to first result.

  • Up to 275 samples processed in 8 hours.

  • Up to 750 samples processed in 16 hours.

Sample capacity:

  • 120 sample tubes in 8 racks with continuous access.

Waste capacity:

  • Can process up to 750 tests before unloading waste.

Component dimensions (w x d x h):

  • Panther system     

122 cm (48 in) x 81.5 cm (32 in) x 175 cm (69 in)

  • UPS (Optional) 

21.4 cm (8.4 in) x 41.0 cm (16.1 in) x 32.5 cm (12.8 in)


  • Panther system     

363 kg (800 lbs)

  • UPS (Optional) 

34.5 kg (76 lbs)

Sample tube barcode types:

  • Code 39, Code 93, Code  28 (ISBT 128), Interleaved 2 of 5, and Codabar.

Environmental requirements:

  • Ambient temperature    

15°C - 30°C

  • Relative humidity

20% - 85%

Electrical requirements:

  • Electrical input 

100-230 +/- 10% vac , 50-60Hz, single phase

  • Current input     

Minimum of 15 amp circuit (dedicated); 20 amp circuit (dedicated) if used with optional UPS

  • Current draw 

Instrument and ancillaries draw 400 watts in power-save mode to 1400 watts peak
- 100 vac circuit draws 14 amps
- 230 vac circuit draws 6 amps

System output:

  • Heat dissipation

550 watts (1878 btu/hour) during steady state

  • Drain output

None: waste fluids drain to removable containers

Performance Data

The Panther system can process up to 275 tests per 8-hour shift, and up to 750 tests in 16 hours. To provide maximum flexibility and menu expansion, the system has been designed for both end-point and real-time assays. The reaction tube takes approximately 3.5 hours to journey through the system for endpoint assays, and approximately 2.5 hours for real-time assays,* before a result is produced. Every five minutes, five additional results are generated. With its impressive level of automation, the design should help improve the efficiency of a typical 8-hour workday, with up to 4 hours of result processing labor-free. The Panther system will continue generating results unattended, providing the maximized productivity that molecular labs need and have been waiting for.

*Functionality currently in development.


PANTHER - The next step in the evolution of molecular diagnostics

Fluid Management
Fluid Management
Internal Modules
Internal Modules
Loading MTUs
Loading MTUs
Waste Management
Waste Management
Load Reagents
Load Reagents
Positive Sample ID
Positive Sample ID
TCR Addition
TCR Addition
Liquid Level Sensing
Liquid Level Sensing
TC Hybridization
TC Hybridization
Transcription Mediated Amplification (TMA)
Transcription Mediated Amplification (TMA)
Probe and Selection Reagent Addition
Probe and Selection Reagent Addition
Reagent Dispense Verification
Reagent Dispense Verification
Sequence Detection
Sequence Detection
Penetrable Cap Technology
Penetrable Cap Technology